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Some people trying to lose weight have gone on the "Atkins diet," in which they eat mostly high-protein, low-carbohydrate foods such as meat, cheese, and eggs. The amino acids in these protein-rich diets, such as alanine, glycine, and serine, can be converted to pyruvate by deamination (removal of the amino group) . Based on this scenario as well as your knowledge of cellular respiration, how many ATP, NADH, and FADH2 molecules will be generated from one molecule of alanine during the mitochondrial matrix reactions?


A) one FADH2, four NADH, and one ATP
B) two FADH2, six NADH, and two ATP
C) no FADH2, one NADH, and two ATP
D) two FADH2, three NADH, and two ATP
E) one FADH2, one NADH, and one ATP

F) D) and E)
G) C) and D)

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When oxygen is present:


A) most animal cells utilize aerobic cellular respiration.
B) most animal cells carry on fermentation and produce lactate.
C) most bacteria and yeasts carry on fermentation.
D) two ATP molecules are produced for each glucose molecule.
E) most animals convert CO2 to glucose.

F) B) and C)
G) B) and D)

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Which of the following processes requires oxygen?


A) glycolysis
B) the Krebs cycle
C) the electron transport chain
D) fermentation

E) None of the above
F) B) and C)

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Chemiosmosis in mitochondria directly results in the synthesis of:


A) NADH.
B) FADH2.
C) H2O.
D) acetyl CoA.
E) ATP.

F) All of the above
G) A) and B)

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If no oxygen is available to a cell, then the net ATP production resulting from the metabolism of a single glucose molecule is:


A) no ATP.
B) one ATP molecule.
C) two ATP molecules.
D) 34 or 36 ATP molecules.
E) 34 or 38 ATP molecules.

F) C) and D)
G) B) and E)

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The inner membrane of the mitochondria can be compared functionally to the thylakoid membranes of the chloroplast because both contain a system for:


A) enzyme synthesis.
B) pyruvate production.
C) glucose synthesis.
D) anaerobic respiration.
E) electron transport.

F) A) and E)
G) C) and E)

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As a bicyclist pedals up a hill to the finish line of a race and "feels the burn" in his leg muscles, those muscle cells are most likely utilizing:


A) only cellular respiration for maximum ATP production.
B) only oxygen for maximum ATP production.
C) some lactate fermentation.
D) both cellular respiration and oxygen for maximum ATP production.

E) B) and C)
F) A) and D)

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In the mitochondrial matrix, oxygen combines with ________ to form ________.


A) electrons only; water
B) hydrogen ions only; water
C) electrons and hydrogen ions; water
D) carbon only; CO2
E) electrons and carbon; CO2

F) All of the above
G) B) and E)

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The electron transport chain receives electrons directly from:


A) NADH only.
B) FADH2 only.
C) ATP only.
D) NADH and FADH2.
E) NADH and ATP.

F) A) and B)
G) A) and C)

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All of the following are true statements about ATP EXCEPT that it is:


A) a short-term energy-storage compound.
B) the cell's principal compound for energy transfers.
C) synthesized only within mitochondria.
D) the molecule that all living cells rely on to do work.

E) B) and D)
F) B) and C)

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The end product of glycolysis is:


A) two pyruvate molecules.
B) two citric acid molecules.
C) one G3P molecule.
D) one lactate molecule.
E) two NAD+ molecules.

F) A) and B)
G) C) and E)

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In vertebrate animal cells, where does the synthesis of lactate occur?


A) fluid portion of the cytoplasm
B) surface of ribosomes
C) mitochondrial matrix
D) mitochondrial inner membranes
E) nucleus

F) A) and B)
G) C) and D)

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The products of the Krebs cycle include:


A) ATP only.
B) carbon dioxide only.
C) energy carriers only.
D) carbon dioxide and energy carriers only.
E) ATP, carbon dioxide, and energy carriers.

F) B) and E)
G) None of the above

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Why is it important that NAD+ molecules are regenerated during fermentation?

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Glycolysis would stop when all...

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During glycolysis, two ATP molecules are "spent" in order to convert glucose to the highly reactive molecule:


A) glyceraldehyde 3-phosphate.
B) FADH2.
C) NADH.
D) fructose bisphosphate.
E) pyruvate.

F) None of the above
G) A) and B)

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Which of the following is an example of an electron-carrier molecule?


A) citric acid
B) CO2
C) acetyl CoA
D) NADH
E) ATP

F) C) and E)
G) B) and C)

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________ is the first stage in glucose metabolism and does not require oxygen.

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During the fermentation of one molecule of glucose, the net production of ATP is:


A) one molecule.
B) two molecules.
C) three molecules.
D) six molecules.
E) eight molecules.

F) B) and D)
G) A) and B)

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Which of the following processes occurs in the cytoplasm?


A) glycolysis
B) the Krebs cycle
C) the electron transport chain

D) None of the above
E) All of the above

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Which kind of metabolic poison would interfere with glycolysis?


A) an agent that reacts with oxygen and depletes its concentration in the cell
B) an agent that binds to pyruvate and inactivates it
C) an agent that closely mimics the structure of glucose but is not capable of being metabolized
D) an agent that reacts with NADH and oxidizes it to NAD+
E) an agent that inhibits the formation of acetyl coenzyme A

F) A) and E)
G) A) and D)

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