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"Mad cow disease" (variant Creutzfeldt-Jakob disease) is caused by a


A) fungus.
B) protozoan.
C) prion.
D) virus.
E) bacterium.

F) B) and C)
G) C) and D)

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Fungi are


A) eukaryotic cells with a cell wall.
B) prokaryotic cells.
C) multicellular parasites that reside within a host.
D) protozoans lacking a cell wall.
E) viruses that are fragments of infectious proteins.

F) A) and B)
G) None of the above

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After maturation, T lymphocytes tend to remain in the same lymphatic structure for life.

A) True
B) False

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The microglia of the brain are macrophages.

A) True
B) False

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The clumping of foreign cells that occurs when antibodies cross-link their antigens is known as


A) agglutination.
B) neutralization.
C) precipitation.
D) opsonization.
E) fixation.

F) A) and C)
G) B) and D)

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Helper T-lymphocytes are also known as


A) cytotoxic T-lymphocytes.
B) CD8+ cells.
C) CD4+ cells.
D) T8 cells.
E) memory T-lymphocytes.

F) B) and E)
G) A) and D)

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"Booster" shots are required following certain vaccinations because the memory B-lymphocytes produced in response to the initial vaccination don't survive indefinitely.

A) True
B) False

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Which type of cell attacks a variety of unwanted cells and causes those cells to undergo apoptosis?


A) Natural killer cells
B) Basophils
C) Neutrophils
D) Eosinophils
E) Macrophages

F) All of the above
G) A) and C)

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Acquired immunity is a system in which lymphocytes respond to particular antigens they encounter during a lifetime. Another name for acquired immunity is ________ immunity.

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Both active and passive immunity can be acquired though natural or artificial means.

A) True
B) False

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Helper T-lymphocyte activation involves MHC class I, whereas cytotoxic T-lymphocyte activation involves MHC class II.

A) True
B) False

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Which type of cell responds to multiple antigens?


A) Memory B-lymphocyte
B) Memory T-lymphocyte
C) Natural killer cell
D) Plasma cell
E) Cytotoxic T-lymphocyte

F) B) and D)
G) B) and E)

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Cytotoxic T-lymphocytes destroy infected cells by releasing


A) antibodies.
B) bradykinin and histamine.
C) perforin and granzymes.
D) CD4+.

E) None of the above
F) A) and B)

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Cytokines are agents that affect neighboring cells without triggering systemic effects.

A) True
B) False

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Malaria is a disease caused by a


A) multicellular parasite.
B) protozoan.
C) fungus.
D) virus.
E) bacterium.

F) D) and E)
G) A) and D)

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Upon activation, a T-lymphocyte


A) ceases dividing and becomes a plasma cell.
B) ceases dividing and becomes a memory cytotoxic helper cell.
C) proliferates to form clones and memory cells.
D) proliferates to form B cells and plasma cells.

E) B) and D)
F) C) and D)

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Which type of cell produces and secretes antibodies?


A) Memory B-lymphocyte
B) Memory T-lymphocyte
C) Natural killer cell
D) Plasma cell
E) Cytotoxic T-lymphocyte

F) B) and E)
G) None of the above

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The primary goal of the immune response is


A) destruction or inactivation of pathogens and foreign material.
B) maintenance of the proper ionic balance between lymph and blood.
C) stimulation of mitotic activity in order to replace cells damaged by infection.
D) reduction of the number of circulating memory lymphocytes.
E) removal of antibodies from lymph and lymphatic organs.

F) A) and B)
G) A) and E)

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One way in which complement defends against bacteria is by binding to it and facilitating phagocytosis. This process is known as ________.

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Which class of major histocompatibility molecules is specific to antigen-presenting cells?


A) MHC class I
B) MHC class II

C) A) and B)
D) undefined

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