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One of the least complicated of the endocrine control systems directly responds to changing blood levels of ions and nutrients. Which of the following describes this mechanism?


A) humoral stimulation
B) protein synthesis
C) catabolic inhibition
D) carbohydrate oxidation

E) None of the above
F) C) and D)

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  Figure 16.1Using Figure 16.1, match the following: -Produces hormones and is considered a neuroendocrine organ. Figure 16.1Using Figure 16.1, match the following: -Produces hormones and is considered a neuroendocrine organ.

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ACTH stimulates the adrenal cortex to release corticosteroid hormones.

A) True
B) False

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Many hormones synthesized in the gastrointestinal tract are chemically identical to brain neurotransmitters.

A) True
B) False

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Mrs. James appeared at the clinic complaining of extreme nervousness and sweating, saying that she could feel and hear her heart thumping when she tried to sleep at night.She was found to have a severely elevated and fluctuating blood pressure. Although laboratory testing revealed hyperglycemia and increased basal metabolic rate, tests of thyroid function were normal. What is your diagnosis? What treatment should be used?

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The diagnosis is hypersecretio...

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The second- messenger mechanism of hormone action operates by .


A) binding to specific receptors and employing the services of G proteins and cAMP
B) synthesizing more than one hormone at a time
C) increasing the basal metabolic rate in the target organ
D) altering gene expression in the nuclear DNA

E) C) and D)
F) A) and B)

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  Figure 16.1Using Figure 16.1, match the following: -Produces the hormones that promote the development of the female secondary sexual characteristics at puberty. Figure 16.1Using Figure 16.1, match the following: -Produces the hormones that promote the development of the female secondary sexual characteristics at puberty.

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Direct gene activation involves a second- messenger system.

A) True
B) False

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Virtually all of the protein or amino acid- based hormones exert their effects through intracellular )


A) nucleotides
B) calcium
C) second messengers
D) deactivating ions

E) A) and C)
F) C) and D)

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The most important mineralcorticoid regulator of electrolyte concentrations in extracellular fluids is .


A) insulin
B) glucagon
C) aldosterone
D) cortisol

E) B) and C)
F) A) and D)

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What ion is sometimes used as a second messenger of amino acid-based hormones?


A) sodium
B) calcium
C) iron
D) chlorine

E) C) and D)
F) All of the above

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Thomas is a diabetic. While at work, he began to tremble, was somewhat disoriented, and showed signs similar to that of a drunk. One of his colleagues gave him some hard candy, which seemed to help him return to normal functions. Why? Was this a proper action, considering that Thomas is diabetic?

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Thomas was suffering from hypoglycemia. ...

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Regulating hormones from the hypothalamus .


A) first enter into the hypophyseal portal system
B) enter the hepatic portal system, which feeds the pituitary
C) enter venous circulation and travel to the heart, which pumps the hormone- containing blood to the pituitary
D) travel by arteries to the pituitary

E) B) and C)
F) None of the above

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  Figure 16.3Using Figure 16.3, match the following: -Produces aldosterone. Figure 16.3Using Figure 16.3, match the following: -Produces aldosterone.

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The prime metabolic effect of cortisol is gluconeogenesis.

A) True
B) False

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Briefly discuss target cell activation by hormone- receptor interaction.

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The first step is hormone- receptor bind...

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A man has been told that he is not synthesizing enough follicle- stimulating hormone (FSH) , and for this reason he may be unable to father a child. Choose the correct statement to explain this problem.


A) FSH stimulates sperm production in the testes.
B) FSH stimulates estrogen secretion by ovarian cells; therefore it is not synthesized by males.
C) The man must be producing progesterone, which inhibits the synthesis of FSH.
D) A hormone made in the adenohypophysis cannot influence fertility.

E) All of the above
F) A) and B)

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John is a 26- year- old man who begins to notice a progressive enlargement of feet, hands, cranium, nose, and lower jaw bone. His doctor recommends a pituitary gland operation. What is the most likely diagnosis? Why?

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The diagnosis is acromegaly. T...

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Which of the following is not a parathyroid gland mechanism to maintain adequate levels of blood calcium?


A) increase calcium ion reabsorption by the kidneys
B) increase in intestinal absorption of calcium ions
C) inhibition of calcitonin synthesis
D) activation of osteoclasts

E) None of the above
F) A) and B)

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Cellular responses to hormones that initiate second- messenger systems include .


A) possible activation of several different second- messenger systems
B) hormone binding to intracellular receptors
C) formation of a specific protein kinase that acts on a series of extracellular intermediates
D) cyclic AMP phosphodiesterase formation of an active second messenger

E) A) and B)
F) A) and C)

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