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Calcium ions (Ca²⁺) are present in the endoplasmic reticulum at concentrations 1,000 times higher than in the cytosol (the gel-like part of the cell outside organelles) .One protein on the endoplasmic reticulum membrane is devoted to allowing Ca²⁺ to move from the endoplasmic reticulum to the cytosol,and another protein moves Ca²⁺ from the cytosol to the endoplasmic reticulum.These processes are not trivial-Ca²⁺ released into the cytosol allows,for example,for muscle contraction and communication between nerve cells.In this pair of Ca²⁺ transport proteins,you would predict that the protein moving Ca²⁺ from the endoplasmic reticulum to the cytosol ________,and the protein that moves Ca²⁺ from cytosol to the endoplasmic reticulum ________.


A) transports calcium slowly; transports calcium rapidly
B) works without ATP; requires ATP
C) requires ATP; works without ATP
D) is large; is small
E) is small; is large

F) A) and D)
G) B) and D)

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Integral proteins always extend completely through the plasma membrane.

A) True
B) False

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The 1985 Nobel Prize in Physiology or Medicine was awarded to Michael Brown and Joseph Goldstein for their work on cholesterol metabolism.Brown and Goldstein investigated the cause of remarkably high levels of circulating cholesterol found in certain families.Just as remarkable was the high incidence of heart disease in these families.What Brown and Goldstein found was not what might be expected-these individuals did not make too much cholesterol.Instead,most of these people had defects in receptor-mediated endocytosis (RME) .What could possibly link high cholesterol levels in the blood and defective RME in these patients?


A) Cholesterol was being secreted from cells by RME at too high a rate and therefore accumulated in the blood.
B) Cholesterol was not transported into cells by RME and therefore accumulated in the blood.
C) Cholesterol was being secreted by facilitated diffusion at too high a rate and therefore accumulated in the blood.
D) Cholesterol was not transported into cells by active transport proteins and therefore accumulated in the blood.
E) Cholesterol was not transported into cells by facilitated diffusion and therefore accumulated in the blood.

F) C) and E)
G) A) and E)

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If you transferred a phospholipid bilayer from water to oil,what effect would this have on the membrane?


A) The membrane would become very rigid.
B) The membrane would form four layers instead of its normal two.
C) The membrane would be unaffected by the oil.
D) The membrane would invert its normal structure by positioning the heads on the inside of the bilayer and the fatty-acid tails outside.
E) The phospholipid bilayer would split into two separate layers, which each would be maintained in the oil.

F) B) and C)
G) C) and E)

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The central vacuoles of some plant cells you are studying fill with water and press the cell contents against their cell walls because of osmosis.What can you predict about the concentration of solutes in the solution that bathes the turgid plant cells?


A) The concentration of solutes outside the cell must be significantly lower than the concentration within the cell.
B) The concentration of solutes outside the cell must be significantly higher than the concentration within the cell.
C) There must be no solutes either outside or inside the cell.
D) The concentration of solutes outside the cell must be about the same as that of seawater.
E) The concentration of solutes outside the cell can't be predicted, because it's the concentration inside the cell that's important.

F) C) and D)
G) A) and B)

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Osmosis is an example of passive transport.

A) True
B) False

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The plasma membrane is composed of phospholipids,which are free to move laterally,and is peppered with both stationary and mobile proteins.This view of the plasma membrane is known as the:


A) peppered membrane model.
B) phospholipid bilayer model.
C) fluid-mosaic model.
D) semipermeable membrane model.

E) All of the above
F) B) and C)

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A main function of the carbohydrates that form the glycocalyx is to:


A) move large molecules in and out of the cell.
B) regulate water movement into the cell.
C) bind cell membranes to the cytoskeleton.
D) act as binding sites for signaling molecules.
E) maintain the proper fluidity of the plasma membrane.

F) A) and C)
G) All of the above

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The ________ of a phospholipid molecule will seek water,whereas the ________ of the molecules will avoid water.


A) tail; head
B) head; tail
C) hydrophobic portion; hydrophilic portion
D) fatty acid; phosphate group

E) None of the above
F) A) and D)

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The plasma membrane is a semipermeable membrane.This means that it is:


A) permeable to small molecules except water.
B) permeable to small and uncharged molecules but not to larger or charged substances.
C) only permeable to cholesterol.
D) permeable to large charged molecules but not to small uncharged molecules.

E) None of the above
F) All of the above

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Membrane proteins perform all of the following functions except:


A) structural support.
B) cell recognition.
C) communication.
D) transport.
E) maintainance of membrane fluidity.

F) A) and B)
G) B) and D)

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Active transport:


A) moves only large molecules into the cell.
B) causes the production of ATP within the cell.
C) increases the concentration of solute inside the cell.
D) moves substances against their concentration gradient.

E) A) and C)
F) A) and B)

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Signals sent between cells reach a cell at receptor proteins.

A) True
B) False

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The ________ functions in cell lubrication,adhesion,and signaling.

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Cholesterol helps to maintain the correct fluidity of the plasma membrane.

A) True
B) False

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Red blood cells placed in pure water will swell and burst.What process is causing this to happen?


A) Water is diffusing across the plasma membrane from a region of high (outside the cell) to low (inside the cell) "free" water concentration.
B) Water is being pulled into the cell by the cell's solutes.
C) Water is diffusing across the plasma membrane from a region of low (outside the cell) to high (inside the cell) "free" water concentration.
D) Solutes are being drawn into the cell across the plasma membrane.
E) Ions are diffusing across the plasma membrane and destabilizing the phospholipids.

F) B) and E)
G) A) and D)

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The outer living limit of the cell is called the:


A) cell wall.
B) edge.
C) plastid.
D) plasma membrane.

E) All of the above
F) None of the above

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Cholesterol is a hormone receptor in the plasma membrane.

A) True
B) False

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Diffusion is a process by which a substance:


A) goes from lesser to greater concentration.
B) goes down its concentration gradient.
C) goes up its concentration gradient.
D) is at equilibrium.

E) B) and C)
F) A) and D)

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A substance moving down the concentration gradient is an example of active transport.

A) True
B) False

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