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Which statement is false about 5,6,7,8-tetrahydrobiopterin?


A) It is required by the enzyme that catalyzes the synthesis of nitric oxide from arginine.
B) It is synthesized by animals and other organisms.
C) It is used in the transfer of phosphate groups during DNA synthesis.
D) It is a reducing agent in the conversion of phenylalanine to tyrosine.

E) B) and C)
F) A) and C)

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What is another name for vitamin B1?


A) Biotin.
B) Thiamine.
C) Lipoamide.
D) Pyridoxal phosphate.

E) B) and D)
F) B) and C)

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What is another name for vitamin B12?


A) Thiamine.
B) Tetrahydrofolate.
C) Cobalamin.
D) Biotin.

E) B) and D)
F) A) and B)

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Which metabolic function depends on Coenzyme A?


A) Oxidation of fuel molecules.
B) Synthesis of DNA.
C) Synthesis of guanine.
D) Conversion of ATP to ADP.

E) None of the above
F) A) and B)

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Why has dihydrofolate reductase been identified as a potential target for chemotherapy in the treatment of cancer?


A) It is a hormone that is a primary control agent of the rate of mitosis.
B) It is a DNA binding protein that activates a cancer oncogene.
C) It is essential in DNA synthesis.Cell division will not occur without it.
D) It selectively binds to a receptor on the surface of cancer cells and inactivates them.

E) A) and C)
F) A) and B)

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The reactive center of CoA is the -NH₃+ group.

A) True
B) False

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Which atom is the reactive center on biotin? Which atom is the reactive center on biotin?   A) Arrow 1 B) Arrow 2 C) Arrow 3 D) Arrow 4


A) Arrow 1
B) Arrow 2
C) Arrow 3
D) Arrow 4

E) C) and D)
F) A) and D)

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Ca++ or Mg++ are most likely to be part of ________,while Zn++ or Fe++ are present in ________.


A) metal-activated enzymes;metalloenzymes
B) metalloenzymes;metal-activated enzymes
C) cofactors;coenzymes
D) coenzymes;cofactors
E) apoenzymes;holoenzymes

F) B) and C)
G) D) and E)

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Another name for vitamin K is phylloquinone.

A) True
B) False

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The structure shown below is which coenzyme? The structure shown below is which coenzyme?   A) QHâ‚‚. B) Vitamin B<sub>12</sub>. C) Biotin. D) Thiamine pyrophosphate.


A) QHâ‚‚.
B) Vitamin B12.
C) Biotin.
D) Thiamine pyrophosphate.

E) C) and D)
F) B) and C)

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An internal aldimine forms when PLP is covalently bound to its enzyme.

A) True
B) False

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Which are common protein coenzymes?


A) Cytochromes.
B) Phylloquinones.
C) Tetrahydrofolates.
D) α-tocopherols .

E) C) and D)
F) All of the above

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Match each of the following vitamins with an associate nutritional deficiency disease. -Folate


A) Pernicious anemia
B) anemia
C) Dermititis in humans
D) scurvy
E) beriberi

F) B) and E)
G) A) and E)

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