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Interest in the efficiency of polyphasic sleep was stimulated by stories of


A) Leonardo da Vinci.
B) Michelangelo.
C) Titian.
D) Hebb.
E) Picasso.

F) A) and B)
G) A) and D)

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There are three classes of drugs that influence sleep: hypnotics, antihypnotics, and a third class that


A) is derived from benzodiazepines.
B) includes melatonin.
C) comprises drugs that influence the circadian rhythmicity of sleep without increasing or decreasing it.
D) all of the above
E) both B and C

F) C) and E)
G) A) and D)

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Neurons of the nucleus magnocellularis


A) normally control muscle relaxation during REM sleep.
B) are active during attacks of cataplexy.
C) are the only cells of the caudal reticular formation that are not active during epileptic attacks.
D) both A and B
E) both B and C

F) C) and D)
G) A) and B)

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The stage of sleep EEG that follows the second bout of stage 2 sleep during a normal night's sleep is


A) emergent stage 3.
B) initial stage 1.
C) emergent stage 1.
D) emergent stage 2.
E) stage 3.

F) A) and B)
G) C) and E)

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After an entire week of REM-sleep deprivation, about how many times in one night did volunteers have to be awakened to prevent them from experiencing bouts of REM sleep?


A) 0
B) 5
C) 17
D) 25
E) 67

F) A) and D)
G) C) and E)

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Melatonin is synthesized from


A) serotonin.
B) acetylcholine.
C) glutamate.
D) GABA.
E) dopamine.

F) None of the above
G) B) and E)

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Injections of the serotonin precursor, 5-hydroxytryptophan,


A) reverse the insomnia produced in cats or rats by the serotonin antagonist PCPA.
B) reverse the sleep increases produced in mice by PCPA.
C) are effective in the treatment of human insomnia.
D) are effective in the treatment of hypersomnia
E) reverse the increases in delta sleep produced in volunteers by sleep reduction.

F) B) and D)
G) A) and B)

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Clock is a circadian gene; it was discovered in


A) mice.
B) sunflowers.
C) dogs.
D) humans.
E) monkeys.

F) A) and B)
G) C) and D)

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Adaptation theories of sleep assume that we are programmed to sleep at night


A) only if we expend energy during the day.
B) only if we expend more energy than we consume during the day.
C) only if we do not sleep during the day.
D) regardless of what we do during the day.
E) only if we eat three times per day.

F) B) and E)
G) A) and B)

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The following is a prediction of many recuperation theories of sleep:


A) Long periods of wakefulness will produce physiological and behavioral disturbances.
B) The disturbances produced by sleep deprivation will grow worse as the deprivation continues.
C) After a period of sleep deprivation, most missed sleep will be regained.
D) all of the above
E) both A and C

F) All of the above
G) None of the above

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Describe three major discoveries about circadian rhythms.Explain why these particular discoveries are so important?

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75% for describing three impor...

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The cortical EEG of cerveau isolΓ© cats is indicative of


A) almost continuous SWS.
B) almost continuous REM sleep.
C) alternating periods of SWS and REM sleep.
D) alternating periods of sleep and wakefulness.
E) the arousing effects of reticular formation damage.

F) C) and E)
G) A) and B)

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Studies of encephalitis lethargica suggested that the


A) the anterior hypothalamus promotes sleep.
B) posterior hypothalamus promotes wakefulness.
C) basal forebrain promotes REM sleep.
D) basal forebrain inhibits REM sleep.
E) both A and B

F) A) and E)
G) B) and C)

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One of the most important features of sleep is that its efficiency increases in response to


A) sleep reduction.
B) cognitive overload.
C) light.
D) tricyclic antidepressants.
E) stress.

F) A) and B)
G) B) and C)

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The pineal gland is located on the midline just below the posterior portion of the


A) corpus callosum.
B) hypothalamus.
C) cerebellum.
D) amygdala.
E) hippocampus.

F) A) and C)
G) C) and E)

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The finding that sleep becomes more efficient in people who regularly sleep less is a key finding because it indicates that


A) sleep-deprivation studies can indicate how much sleep people need only if the volunteers who are being studied are efficient sleepers.
B) sleep is a positive incentive.
C) sleep can be made more efficient by reinforcements and punishments.
D) only circadian theories can account for the negative effects of sleep deprivation.
E) sleep can be conditioned.

F) A) and D)
G) All of the above

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Some antidepressant drugs can block __________ sleep for months at a time without having obvious related adverse effects.

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The association of REM sleep and dreaming was discovered in the early 1950s in the laboratory of


A) Siegel.
B) Kleitman.
C) Mistlberger.
D) Meddis.
E) Freud.

F) C) and D)
G) A) and E)

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It is impossible for a human to stay awake longer than __________ hours without experiencing life-threatening physiological problems.


A) 24
B) 36
C) 48
D) 60
E) none of the above

F) C) and D)
G) A) and B)

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A large group of patients who sought treatment for insomnia were found in one study to sleep __________ hours per night.


A) 2.5
B) 3.5
C) 4.5
D) 5.5
E) 6.5

F) D) and E)
G) A) and B)

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