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Which two mature blood cell types descend from myeloblasts?


A) T cells and B cells
B) Erythrocytes and platelets
C) Neutrophils and basophils
D) Monocytes and lymphocytes

E) All of the above
F) B) and C)

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A patient is suffering from a condition requiring multiple blood transfusions. They have type A blood and their first transfusion was perfectly successful. However, their second transfusion of type A blood causes them to become very ill and observation of their blood reveals agglutination. What has happened to cause their second transfusion to fail?


A) The blood used in the first transfusion contained Rh antigens, which caused the patient to produce anti-Rh antibodies and attack the blood from the second transfusion.
B) They have developed a sensitivity to A antigens after being exposed to the first transfusion.
C) The second transfusion must have had anti-A antibodies, which began attacking their blood.
D) The blood used in the second transfusion must have come from a pregnant woman with Rh-negative blood.

E) A) and B)
F) All of the above

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A patient comes to the hospital with a suspected case of MRSA (a dangerous bacterial infection) . Which of the following blood components would you expect to show elevated numbers in a blood test?


A) Red blood cells
B) Eosinophils
C) Neutrophils
D) Monocytes

E) B) and C)
F) C) and D)

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C

A child is born with a genetic mutation in which the plasminogen protein is absent in blood plasma. How will this affect hemostasis?


A) Plasminogen activates Factor III to begin the extrinsic clotting mechanism, so clotting will be prevented.
B) Blood clots will not be dissolved because plasminogen becomes a clot-dissolving substance.
C) Clotting will be prevented because plasminogen activates Hageman Factor to begin the intrinsic clotting mechanism.
D) Plasminogen causes platelets to adhere to collagen in the broken surfaces of blood vessels, so the platelet plug will not form.

E) None of the above
F) B) and D)

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The hormone released form the kidneys that promotes the production of red blood cells is ________.

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Pus is composed of


A) neutrophils, eosinophils, and basophils.
B) bacteria, white blood cells, and damaged cells.
C) mucus, sputum, and platelets.
D) water, serum, and fibers.

E) B) and D)
F) All of the above

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A red blood cell contains a large nucleus; it is thicker near the center and thin around the rim of the cell.

A) True
B) False

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Thrombocytopenia is due to a deficiency of


A) vitamin K.
B) platelets.
C) leukocytes.
D) factor VII.

E) A) and D)
F) A) and C)

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The percentage of red blood cells in a sample of human blood is normally about


A) 15%.
B) 30%.
C) 45%.
D) 60%.

E) A) and C)
F) B) and D)

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Heme released from hemoglobin in aged red blood cells is decomposed in the liver into


A) iron and the bile pigment biliverdin, which is eventually converted to bilirubin.
B) iron and the bile pigment bilirubin, which is eventually converted to biliverdin.
C) iron and interleukins.
D) serum and plasma proteins.

E) A) and D)
F) B) and D)

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Nonprotein nitrogenous substances include


A) cholesterol.
B) red blood cells.
C) creatinine.
D) calcium ions.

E) B) and D)
F) A) and B)

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Which is the correct sequence for differentiation of a red blood cell?


A) Hematopoietic stem cell, erythrocyte, hematoblast, erythroblast
B) Hematopoietic stem cell, erythroblast, erythrocyte, reticulocyte
C) Hematopoietic stem cell, hemocytoblast, erythrocyte, erythroblast
D) Hematopoietic stem cell, erythroblast, reticulocyte, erythrocyte

E) A) and C)
F) C) and D)

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Tom has a condition in which the endothelial lining of his blood vessels cannot secrete prostacyclin (PGI₂) . How will this affect his blood?


A) Because prostacyclin is a clotting factor that encourages formation of platelet plugs, bleeding will not be slowed.
B) Prostacyclin is involved in the activation of prothrombin, so the process of clotting will not be complete.
C) Prostacyclin is a clot-dissolving enzyme, so clots will not be broken down and Tom will be at risk for an embolism or thrombosis.
D) Because prostacyclin prevents platelets from sticking to the inside of healthy blood vessels, Tom will experience clotting and general narrowing of the blood vessels.

E) B) and D)
F) All of the above

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In an adult, red blood cells are produced primarily in the ________.

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Athletes abuse erythropoeitin (EPO) because it


A) increases the red blood cell supply, which brings more oxygen to muscle cells.
B) decreases the red blood cell supply, which brings more oxygen to muscle cells.
C) increases the red blood cell supply, which depletes oxygen from muscle cells.
D) increases the white blood cell supply, which prevents infection.

E) None of the above
F) A) and D)

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A condition occurs where the number of basophils in the blood drastically decreases. Which of the following would directly result from the loss of basophils?


A) Bacteria and fungi would not be phagocytized and removed from an infected tissue.
B) Tumors and microorganisms would not be directly attacked by T cells.
C) Increased susceptibility to parasitic infections and loss of allergic responses would occur.
D) Wound areas won't produce an inflammatory reaction and attract an immune response from defensive leukocytes.

E) B) and C)
F) B) and D)

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Diapedesis is


A) the formation of platelets from megakaryocytes.
B) filling of red blood cells with hemoglobin.
C) movements of white blood cells out of the circulation.
D) squeezing of red blood cells through narrow capillaries.

E) C) and D)
F) A) and C)

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Persons with type AB blood are sometimes called universal donors.

A) True
B) False

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False

An abnormally low white blood cell count is called ________.

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Vitamin B₁₂ is poorly absorbed in the absence of


A) folic acid.
B) erythropoietin.
C) intrinsic factor.
D) extrinsic factor.

E) A) and D)
F) A) and C)

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C

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