Question 1

Select the components of the eukaryotic preinitiation complex.

Accepted Answer

A)   TFIID
B)   DNA
C)   TFIIB
D)   RNA polymerase II
E)   mediatorF) A) and B)
G) A) and C)

Question 2

Which of the following forms of RNA encodes the sequence of amino acids for a functional protein?

Accepted Answer

A)   tRNA
B)   snRNA
C)   mRNA
D)   rRNA
E)   scRNAF) A) and B)
G) A) and C) C

Question 3

A functional eukaryotic protein is typically made up of the information contained within what region of pre-mRNA?

Accepted Answer

A)   exons
B)   introns
C)   enhancers
D)   promotersE) All of the above
F) None of the above

Question 4

Select the stages of transcription.

Accepted Answer

A)   initiation
B)   elongation
C)   termination
D)   translation
E)   replicationF) B) and C)
G) B) and D) A,B,C

Question 5

In prokaryotes,a holoenzyme is formed when what is added to the core enzyme?

Accepted Answer

A)   Start codons
B)   b
C)   b'
D)   σ
E)   aF) A) and E)
G) B) and C)

Question 6

A mutation in which of the following would result in a failure of the RNA polymerase to maintain an open complex?

Accepted Answer

A)   TFIIB
B)   TFIID
C)   TFIIE
D)   TFIIH
E)   TFIIFF) A) and B)
G) C) and D)

Question 7

What is the purpose of phosphorylating the carboxy terminal domain (CTD) of RNA Polymerase II?

Accepted Answer

A)   convert from the initiation to the elongation stage
B)   to aid in transcriptional initiation
C)   phosphorylate transcription factors
D)   allow transcription factors to bind the TATA boxE) A) and C)
F) None of the above A

Question 8

What enables the splicing of group I and II introns?

Accepted Answer

A)   spliceosomes
B)   ribozymes
C)   snRNA
D)   poly-A tailE) A) and B)
F) A) and C)

Question 9

The RNA polymerase forms a closed complex during the process of elongation during transcription.

Accepted Answer

A) True 
 B)False

Question 10

RNA polymerase I in eukaryotes produces which type of RNA?

Accepted Answer

A)   snRNA
B)   tRNA
C)   5S rRNA
D)   18S rRNAE) B) and C)
F) All of the above

Question 11

During translation,the mRNA is read in groups of nucleotides called quadrons.

Accepted Answer

A) True 
 B)False

Question 12

Which subunit of the prokaryotic RNA polymerase carries out catalytic synthesis of RNA?

Accepted Answer

A)   alpha
B)   omega
C)   beta
D)   sigmaE) A) and B)
F) All of the above

Question 13

In trying to distinguish between the two models of eukaryotic transcriptional termination,you identify a drug that specifically blocks exonuclease activity.When you add it at the appropriate time to an in vitro system that carries out all the stages of eukaryotic transcription,you find that transcription proceeds normally,but transcription doesn't terminate. This experiment provides support for which model of eukaryotic transcriptional termination?

Accepted Answer

A)   Allosteric model
B)   Torpedo model
C)   Rho-dependent termination
D)   Rho-independent terminationE) A) and D)
F) B) and C)

Question 14

Following transcription,the RNA has a complementary sequence to

Accepted Answer

A)   regulatory sequences.
B)   termination sequences.
C)   the coding strand of DNA.
D)   the template strand of DNA.E) B) and C)
F) A) and B)

Question 15

The formation of open complex usually forms in GC-rich regions of DNA due to the decreased number of hydrogen bonds.

Accepted Answer

A) True 
 B)False

Question 16

What region in eukaryotic genes contains the majority of regulatory elements?

Accepted Answer

A)   0 to 50
B)   −50 to 0
C)   −50 to −100
D)   −100 to −150E) B) and D)
F) A) and B)

Question 17

Which of the following is not an example of a eukaryotic regulatory element?

Accepted Answer

A)   enhancers
B)   silencers
C)   core promoters
D)   cis-acting elements
E)   All of the answers are examples.F) A) and C)
G) A) and B)

Question 18

A ribozyme is a catalytic protein that assists in the processing of tRNA.

Accepted Answer

A) True 
 B)False

Question 19

The Prinbow box contains a CACAAC consensus sequence located in the −100 region of the promoter.

Accepted Answer

A) True 
 B)False

Question 20

Basal transcription in eukaryotes involves the action of only the core promoter.

Accepted Answer

A) True 
 B)False

Exam 14: Gene Transcription and RNA Modification

Select the components of the eukaryotic preinitiation complex.

Correct Answer
verified

Which of the following forms of RNA encodes the sequence of amino acids for a functional protein?

Correct Answer
verified
C

A functional eukaryotic protein is typically made up of the information contained within what region of pre-mRNA?

Correct Answer
verified

Select the stages of transcription.

Correct Answer
verified
A,B,C

In prokaryotes,a holoenzyme is formed when what is added to the core enzyme?

Correct Answer
verified

A mutation in which of the following would result in a failure of the RNA polymerase to maintain an open complex?

Correct Answer
verified

What is the purpose of phosphorylating the carboxy terminal domain (CTD) of RNA Polymerase II?

Correct Answer
verified
A

What enables the splicing of group I and II introns?

Correct Answer
verified

The RNA polymerase forms a closed complex during the process of elongation during transcription.

Correct Answer
verified

RNA polymerase I in eukaryotes produces which type of RNA?

Correct Answer
verified

During translation,the mRNA is read in groups of nucleotides called quadrons.

Correct Answer
verified

Which subunit of the prokaryotic RNA polymerase carries out catalytic synthesis of RNA?

Correct Answer
verified

Correct Answer
verified

Following transcription,the RNA has a complementary sequence to

Correct Answer
verified

The formation of open complex usually forms in GC-rich regions of DNA due to the decreased number of hydrogen bonds.

Correct Answer
verified

What region in eukaryotic genes contains the majority of regulatory elements?

Correct Answer
verified

Which of the following is not an example of a eukaryotic regulatory element?

Correct Answer
verified

A ribozyme is a catalytic protein that assists in the processing of tRNA.

Correct Answer
verified

The Prinbow box contains a CACAAC consensus sequence located in the −100 region of the promoter.

Correct Answer
verified

Basal transcription in eukaryotes involves the action of only the core promoter.

Correct Answer
verified

Exam 14: Gene Transcription and RNA Modification

Select the components of the eukaryotic preinitiation complex.

Correct AnswerverifiedShow Answer

Which of the following forms of RNA encodes the sequence of amino acids for a functional protein?

Correct AnswerverifiedC

A functional eukaryotic protein is typically made up of the information contained within what region of pre-mRNA?

Correct AnswerverifiedShow Answer

Select the stages of transcription.

Correct AnswerverifiedA,B,C

In prokaryotes,a holoenzyme is formed when what is added to the core enzyme?

Correct AnswerverifiedShow Answer

A mutation in which of the following would result in a failure of the RNA polymerase to maintain an open complex?

Correct AnswerverifiedShow Answer

What is the purpose of phosphorylating the carboxy terminal domain (CTD) of RNA Polymerase II?

Correct AnswerverifiedA

What enables the splicing of group I and II introns?

Correct AnswerverifiedShow Answer

The RNA polymerase forms a closed complex during the process of elongation during transcription.

Correct AnswerverifiedShow Answer

RNA polymerase I in eukaryotes produces which type of RNA?

Correct AnswerverifiedShow Answer

During translation,the mRNA is read in groups of nucleotides called quadrons.

Correct AnswerverifiedShow Answer

Which subunit of the prokaryotic RNA polymerase carries out catalytic synthesis of RNA?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Following transcription,the RNA has a complementary sequence to

Correct AnswerverifiedShow Answer

The formation of open complex usually forms in GC-rich regions of DNA due to the decreased number of hydrogen bonds.

Correct AnswerverifiedShow Answer

What region in eukaryotic genes contains the majority of regulatory elements?

Correct AnswerverifiedShow Answer

Which of the following is not an example of a eukaryotic regulatory element?

Correct AnswerverifiedShow Answer

A ribozyme is a catalytic protein that assists in the processing of tRNA.

Correct AnswerverifiedShow Answer

The Prinbow box contains a CACAAC consensus sequence located in the −100 region of the promoter.

Correct AnswerverifiedShow Answer

Basal transcription in eukaryotes involves the action of only the core promoter.

Correct AnswerverifiedShow Answer

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C

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A,B,C

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A

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