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Which is the primary adverse reaction associated with the use of benzodiazepines for conscious sedation?


A) Anterograde amnesia
B) Retrograde amnesia
C) Spiking blood pressure
D) Respiratory depression

E) A) and D)
F) All of the above

Correct Answer

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The therapeutic index of benzodiazepines is _____ that of the barbiturates.


A) wider than
B) narrower than
C) the same as
D) None of the above are correct.

E) None of the above
F) A) and C)

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The benzodiazepines are preferable to the barbiturates as hypnotics because the risk of physical addiction or serious poisoning is much less.The efficacy of the benzodiazepines in the treatment of chronic insomnia has been demonstrated for longer than 2 years.


A) Both statements are true.
B) Both statements are false.
C) The first statement is true,the second is false.
D) The first statement is false,the second is true.

E) A) and B)
F) None of the above

Correct Answer

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Which of the following nonbenzodiazepine-benzodiazepine receptor agonists has the shortest half-life?


A) Zolpidem (Ambien)
B) Zaleplon (Sonata)
C) Eszopiclone (Lunesta)

D) A) and C)
E) A) and B)

Correct Answer

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Which is best for all types of anxiety and muscle strain?


A) Barbiturates
B) Meprobamate
C) Benzodiazepines
D) Placebo

E) B) and C)
F) A) and B)

Correct Answer

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Which of the following sleep stages is enhanced with the use of benzodiazepines?


A) Latency period
B) Rapid eye movement (REM) sleep
C) Nonrapid eye movement (NREM) sleep stages 3 and 4
D) Nonrapid eye movement (NREM) sleep stage 2

E) A) and C)
F) A) and B)

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Which of the following are rationales for the use of analgesic-sedative combinations? (Select all that apply. )


A) Relief of both anxiety and pain is often required in one patient.
B) Sedatives interfere with analgesic agents.
C) Sedatives may induce excitation when given without an analgesic to patients with uncontrolled pain.
D) Anxiety can raise the pain threshold.

E) All of the above
F) A) and C)

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Some benzodiazepines are transformed in the body to active metabolites.The active metabolites are formed by phase II drug metabolism.


A) Both statements are true.
B) Both statements are false.
C) The first statement is true,the second is false.
D) The first statement is false,the second is true.

E) B) and C)
F) None of the above

Correct Answer

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Which of the following parenteral benzodiazepines seems to have the greatest likelihood to produce amnesia?


A) Diazepam (Valium)
B) Midazolam (Versed)
C) Triazolam (Halcion)
D) Eszopiclone (Lunesta)

E) None of the above
F) B) and C)

Correct Answer

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Antianxiety agents are most commonly administered orally because the effective dose of a particular antianxiety agent is very predictable.


A) Both statements are true.
B) Both statements are false.
C) The first statement is true,the second is false.
D) The first statement is false,the second is true.

E) C) and D)
F) A) and C)

Correct Answer

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Which of the following agents is a melatonin receptor agonist?


A) Buspirone
B) Zaleplon
C) Chloral hydrate
D) Ramelteon
E) Tizanidine

F) D) and E)
G) C) and D)

Correct Answer

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Chronic use of barbiturates can lead to _____ dependence.


A) both physical and psychologic
B) physical but not psychologic
C) psychologic but not physical
D) neither physical nor psychologic

E) B) and C)
F) A) and D)

Correct Answer

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Benzodiazepines are contraindicated in wide-angle glaucoma.

A) True
B) False

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Which of the following is the longest acting barbiturate?


A) Methohexital (Brevital)
B) Pentobarbital (Nembutal)
C) Secobarbital (Seconal)
D) Phenobarbital (Luminal)

E) A) and C)
F) C) and D)

Correct Answer

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Use of antianxiety agents in the dentist's office should be discouraged because it encourages addiction.

A) True
B) False

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Barbiturates act on nerves by enhancing the binding of which neurotransmitter to its receptor?


A) Glutamate
B) Serotonin
C) GABA
D) Chloride

E) A) and B)
F) A) and C)

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Benzodiazepines enhance or facilitate the action of the neurotransmitter


A) acetylcholine.
B) epinephrine.
C) g-aminobutyric acid (GABA) .
D) serotonin.

E) B) and C)
F) None of the above

Correct Answer

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Which of the following agents may decrease the effectiveness of benzodiazepines?


A) Tobacco
B) Omeprazole
C) Valproic acid
D) Fluoxetine

E) A) and B)
F) A) and C)

Correct Answer

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______ is an intravenously (IV) administered benzodiazepine that is used for conscious sedation in oral health care.


A) Chlordiazepoxide (Librium)
B) Lorazepam (Ativan)
C) Triazolam (Halcion)
D) Midazolam (Versed)

E) B) and C)
F) A) and D)

Correct Answer

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Which of the following agents are the most commonly prescribed type of antianxiety drugs?


A) Nonbenzodiazepine-nonbarbiturate sedative-hypnotics
B) Nonbenzodiazepine-nonbarbiturate receptor agonists
C) Benzodiazepines
D) Barbiturates

E) All of the above
F) B) and C)

Correct Answer

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