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Unlike animals,plants lack a cell junction where small molecules can move from one cell to another cell.

A) True
B) False

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An artificial membrane vesicle is mixed with several peripheral membrane proteins and analyzed by freeze-fracture electron microscopy.What will be seen in the resulting image?


A) Bumps will be visible on both layers
B) Bumps will be visible only in the extracellular face (E face)
C) Bumps will be visible in the protoplasmic face (P face)
D) No bumps will be visible in either face

E) A) and D)
F) All of the above

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The best descriptive comparison between hemidesmosomes and desmosomes is


A) hemidesmosomes are anchorage junctions but desmosomes are not.
B) hemidesmosomes are found in plant cells while desmosomes are found in animal cells.
C) both hemidesmosomes and desmosomes associate with integrin,but not cadherin molecules.
D) hemidesmosomes interact with actin filaments while desmosomes interact with intermediate filaments.
E) hemidesmosomes anchor cells to the ECM while desmosomes anchor cells to other cells.

F) D) and E)
G) A) and E)

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Passive diffusion


A) is the process by which molecules move from an area of low concentration to an area of high concentration.
B) is a spontaneous process.
C) requires the presence of a transmembrane protein.
D) will occur so long as the membrane is freely permeable to the solute.
E) requires energy.

F) D) and E)
G) C) and E)

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The plasma membrane Na+/K+-ATPase pump


A) is used to generate sodium and potassium gradients across the membrane.
B) is a symporter.
C) is a pump for active transport of K+ out of the cell and Na+ into the cell.
D) is a pump for facilitated diffusion of K+ into the cell and Na+ out of the cell.
E) does not require ATP.

F) C) and E)
G) All of the above

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A researcher is studying the integral membrane protein "mysteriase" and chooses to perform an experiment similar to that performed by Frye and Edidin.The researcher fuses a mouse cell expressing mysteriase with a human cell.The fused cell is incubated at 37 ∘\circ C prior to being cooled to 0 ∘\circ C and labeled with a fluorescent antibody against mysteriase.When observed with a fluorescent microscope,mysteriase is observed to remain on one side of the fused cell.What is the most likely explanation for this surprising observation?


A) Mysteriase rigidifies the plasma membrane
B) There is an error in the experimental procedure because this result is impossible
C) Mysteriase is bound to the cytoskeletal filament
D) Mouse cells are less fluid than human cells
E) Mysteriase is a flippase enzyme that enhances lipid flip-flop rather than lipid lateral movement

F) None of the above
G) B) and D)

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Imagine that a cell can be treated with a drug that prevents proteins from undergoing large conformational changes.Which transport proteins would be unaffected by this drug treatment?


A) Na+/K+ ATPase
B) H+/sucrose symporter
C) Fructose uniporter
D) Aquaporin
E) All transport proteins would be affected

F) D) and E)
G) A) and E)

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The pressure required to stop water from moving across the membrane by osmosis is called


A) transport pressure.
B) crenation pressure.
C) atmospheric pressure.
D) osmotic pressure.
E) mechanical pressurE.

F) A) and C)
G) A) and B)

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How might a plant cell compensate for the excessive membrane fluidity that occurs during prolonged exposures to elevated temperature?


A) Reduce membrane cholesterol content.
B) Alter the lipid composition to have longer fatty acyl tails and fewer double bonds.
C) Alter the lipid composition to have shorter fatty acyl tails and more double bonds.
D) Alter the lipid composition to have shorter and more unsaturated fatty acyl tails.
E) Reduce cholesterol content and alter the lipid composition to have shorter fatty acyl tails.

F) A) and D)
G) A) and C)

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You inject a dye into a cell and observe that it moves into adjacent cells.This would occur through _____.


A) adherins junctions
B) tight junctions
C) desmosomes
D) plasmodesmata
E) gap junctions

F) B) and E)
G) C) and D)

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________ act as rivets anchoring adjacent cells together at spots throughout the cell.


A) Focal adhesions
B) Desmosomes
C) Adherens junctions
D) Hemidesmosomes
E) Fibronectin

F) A) and E)
G) All of the above

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The movement of sucrose and H+ into the cell by the same membrane protein reflects the actions of what type of transporter?


A) Voltage-gated channel.
B) Mechanosensitive channel.
C) Uniporter.
D) Symporter.
E) Antiporter.

F) A) and B)
G) B) and D)

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A drug company wants to design a medicine that will bind to surface proteins and initiate a conformational change allowing the drug to enter.You suggest the study focus on


A) channels.
B) pumps.
C) transporters.
D) receptors.

E) B) and D)
F) C) and D)

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If contents of the intestines can leak into the blood then ______ must have been damaged.


A) focal adhesions
B) tight junctions
C) desmosomes
D) gap junctions
E) hemidesmosomes

F) A) and D)
G) D) and E)

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Movement of molecules down their concentration gradient can drive the movement of a different molecule against its concentration gradient.

A) True
B) False

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________ bind two or more ions or molecules and transport them in opposite directions across a membrane.


A) Uniporters
B) Symporters
C) Antiporters
D) Dual transporters
E) Channel pumps

F) A) and C)
G) None of the above

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Gap junctions in animal cells are most similar to ________ in plant cells?


A) tight junctions
B) hemidesmosomes
C) plasmodesmata
D) middle lamella
E) primary cell walls

F) B) and D)
G) B) and E)

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Osmosis describes the movement of water from an area of high to low solute concentration.

A) True
B) False

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Cellular membranes are mosaic and


A) fluid.
B) rigid.
C) symmetrical.
D) highly permeable to large molecules.
E) polar.

F) B) and C)
G) A) and C)

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Muscular dystrophy is caused by a mutation in the intracellular dystrophin that normally binds to the cytoskeleton.Dystrophin also binds to _______ ,which is found in the plasma membrane of the cell and binds the extra cellular matrix.


A) a gap junction
B) an integrin
C) a cadherin
D) a tight junction
E) an actin filament

F) B) and C)
G) C) and D)

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