Question 1

The catalytic mechanism of the isomerization of a ketose into an aldose proceeds through an _________________ intermediate.

Accepted Answer

The answer of The catalytic mechanism of the isomerization of...

Question 2

How is the conversion of phosphoenolpyruvate to pyruvate accompanied by ATP formation?

Accepted Answer

The enol phosphate possesses v...

Question 3

What astounding discovery was made by the Buchners?

Accepted Answer

When the Buchners demonstrated...

Question 4

What is the purpose of phosphorylating glucose in the cytosol?

Accepted Answer

A)   to trap glucose in the cell
B)   to destabilize glucose and facilitate the next series of metabolic steps
C)   to convert it to a more soluble form
D)   to slow the transport of glucose into the cell
E)   Both A and B are correct.F) A) and D)
G) A) and E)

Question 5

Which of the following is an allosteric inhibitor of gluconeogenesis?

Accepted Answer

A)   NADH
B)   ATP
C)   AMP
D)   fructose 6-phosphate
E)   phosphoenolpyruvateF) All of the above
G) A) and E)

Question 6

The key enzyme that regulates the pace of glycolysis is ____________________.

Accepted Answer

The answer of The key enzyme that regulates the pace...

Question 7

What two functions are attributed to substrate cycles?

Accepted Answer

The substrate cycles regulate glycolytic path flux by amplifying metabolic signals,and they generate body heat produced by the hydrolysis of ATP.

Question 8

Two primary raw materials for gluconeogenesis in the human liver are

Accepted Answer

A)   galactose and sucrose.
B)   acetate and oxaloacetate.
C)   lactate and alanine.
D)   fructose and alanine.
E)   lactose and lactate.F) All of the above
G) A) and C)

Question 9

What transporter is responsible for fructose uptake in the intestine?

Accepted Answer

A)   GLUT1
B)   GLUT2
C)   GLUT3
D)   GLUT4
E)   GLUT5F) A) and D)
G) D) and E)

Question 10

What reaction is catalyzed by aldolase?

Accepted Answer

A)   isomerization of DHAP to GAP
B)   hydrolysis of either GAP or DHAP
C)   reversible cleavage of F-1,6-BP to DHAP and GAP
D)   cleavage of DHAP to GAP
E)   irreversible aldol condensation of DHAP and GAPF) B) and D)
G) A) and C)

Question 11

Which of the following are reasons that glucose is a common metabolic fuel used by living organisms?

Accepted Answer

A)   In its stable ring structure, glucose is unlikely to nonezymatically glycosylate proteins.
B)   It is one of the fuels formed under prebiotic conditions, thus available for primitive biochemical systems.
C)   It is the only sugar used by the brain and kidney as a fuel source.
D)   It is a ketose and thus a nonreducing sugar.
E)   Both A and B are correct.F) B) and D)
G) B) and C)

Question 12

Which of the following intermediates is needed for the conversion of galactose into glucose by reacting with galactose 1-phosphate?

Accepted Answer

A)   glucose 1-phosphate
B)   fructose 6-phosphate
C)   glucose 6-phosphate
D)   UDP-galactose
E)   UDP-glucoseF) A) and B)
G) A) and C)

Question 13

Why do muscles need to generate ATP under aerobic and anaerobic conditions?

Accepted Answer

Muscles initially function aerobically.H...

Question 14

What nutrient is required for the carboxylation of pyruvate in humans?

Accepted Answer

A)   biotin
B)   thiamine
C)   riboflavin
D)   niacin
E)   folic acidF) B) and C)
G) A) and C)

Question 15

Describe the biochemical explanation for galactosemia.

Accepted Answer

Galactose is metabolized by conversion t...

Question 16

A potent allosteric activator of liver phosphofructokinase is _____________________,which is produced from fructose-6-phosphate by PFK2.

Accepted Answer

fructose-2...

Question 17

What are the primary metabolic fates of pyruvate?

Accepted Answer

A)   ethanol
B)   lactate
C)   acetyl CoA
D)   All of the answers are correct.
E)   ethanol and lactateF) B) and E)
G) A) and B) D

Question 18

Describe the two isoforms of lactate dehydrogenase.

Accepted Answer

Two forms exist,called M and H,which pre...

Question 19

Which of the following must be regenerated for glycolysis to proceed?

Accepted Answer

A)   pyruvate
B)   ATP
C)   NAD+
D)   UDP-glucose
E)   All of the answers are correct.F) B) and D)
G) B) and C)

Question 20

What two 3-carbon molecules are generated by the cleavage of fructose-1,6-bisphosphate?

Accepted Answer

A)   glyceraldehyde-3-phosphate and 3-phosphoglycerate
B)   glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
C)   pyruvate and phosphoenolpyruvate
D)   enolase and 2-phosphoglycerate
E)   glyceraldehyde-3-phosphate and pyruvateF) A) and E)
G) B) and C) B

Exam 16: Glycolysis and Gluconeogenesis

The catalytic mechanism of the isomerization of a ketose into an aldose proceeds through an _________________ intermediate.

Correct AnswerverifiedShow Answer

How is the conversion of phosphoenolpyruvate to pyruvate accompanied by ATP formation?

Correct AnswerverifiedThe enol phosphate possesses v...View AnswerShow Answer

What astounding discovery was made by the Buchners?

Correct AnswerverifiedWhen the Buchners demonstrated...View AnswerShow Answer

What is the purpose of phosphorylating glucose in the cytosol?

Correct AnswerverifiedShow Answer

Which of the following is an allosteric inhibitor of gluconeogenesis?

Correct AnswerverifiedShow Answer

The key enzyme that regulates the pace of glycolysis is ____________________.

Correct AnswerverifiedShow Answer

What two functions are attributed to substrate cycles?

Correct AnswerverifiedThe substrate cycles regulate glycolytic path flux by amplifying metabolic signals,and they generate body heat produced by the hydrolysis of ATP.

Two primary raw materials for gluconeogenesis in the human liver are

Correct AnswerverifiedShow Answer

What transporter is responsible for fructose uptake in the intestine?

Correct AnswerverifiedShow Answer

What reaction is catalyzed by aldolase?

Correct AnswerverifiedShow Answer

Which of the following are reasons that glucose is a common metabolic fuel used by living organisms?

Correct AnswerverifiedShow Answer

Which of the following intermediates is needed for the conversion of galactose into glucose by reacting with galactose 1-phosphate?

Correct AnswerverifiedShow Answer

Why do muscles need to generate ATP under aerobic and anaerobic conditions?

Correct AnswerverifiedMuscles initially function aerobically.H...View AnswerShow Answer

What nutrient is required for the carboxylation of pyruvate in humans?

Correct AnswerverifiedShow Answer

Describe the biochemical explanation for galactosemia.

Correct AnswerverifiedGalactose is metabolized by conversion t...View AnswerShow Answer

A potent allosteric activator of liver phosphofructokinase is _____________________,which is produced from fructose-6-phosphate by PFK2.

Correct Answerverifiedfructose-2...View AnswerShow Answer

What are the primary metabolic fates of pyruvate?

Correct AnswerverifiedD

Describe the two isoforms of lactate dehydrogenase.

Correct AnswerverifiedTwo forms exist,called M and H,which pre...View AnswerShow Answer

Which of the following must be regenerated for glycolysis to proceed?

Correct AnswerverifiedShow Answer

What two 3-carbon molecules are generated by the cleavage of fructose-1,6-bisphosphate?

Correct AnswerverifiedB

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The enol phosphate possesses v...
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When the Buchners demonstrated...
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The substrate cycles regulate glycolytic path flux by amplifying metabolic signals,and they generate body heat produced by the hydrolysis of ATP.

Correct Answer
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Muscles initially function aerobically.H...
View Answer

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Galactose is metabolized by conversion t...
View Answer

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fructose-2...
View Answer

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D

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Two forms exist,called M and H,which pre...
View Answer

Correct Answer
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B