Question 1

The reaction catalyzed by _____ requires an enzyme bound flavin coenzyme.

Accepted Answer

A)  isocitrate dehydrogenase
B)  ( α\alphaα -ketoglutarate dehydrogenase) 
C)  succinyl-CoA synthetase
D)  succinate dehydrogenase
E)  malate dehydrogenase F) B) and E)
G) B) and D)

Question 2

Which of the following coenzymes is required by E1 of the pyruvate dehydrogenase complex for catalytic activity?

Accepted Answer

A)  thiamine pyrophosphate
B)  lipoamide
C)  coenzyme A
D)  NAD+
E)  FADF) B) and D)
G) A) and E)

Question 3

Considering the reactions within the citric acid cycle, which of the following molecules will be produced from the intermediate pictured on the right?

Accepted Answer

A)  citrate
B)  isocitriate
C)  succinate
D)  succinyl-CoA
E)  α-ketoglutarateF) C) and D)
G) A) and E)

Question 4

Which of the following can be said about the isocitrate product of aconitase?

Accepted Answer

A)  The product always has the R configuration.
B)  The product always has the S configuration.
C)  The product is not chiral.
D)  The product can exist in either the R or S configuration in eukaryotes.
E)  If the product is in the R configuration it has by passed the cis-aconitate intermediate.F) A) and D)
G) B) and E)

Question 5

Matching 
Choose the correct answer from the list. Not all the answers will be used.
-The compound ______ is a structural analog and competitive inhibitor of the enzyme succinate dehydrogenase.

Accepted Answer

A)  oxaloacetate
B)  malate synthase
C)  malate
D)  malonate
E)  KrebsF) aconitaseG) succinyl-CoA synthetaseH) α-ketoglutarateI) carbon dioxideJ) malate dehydrogenaseK) isocitrateL) succinate dehydrogenaseM) B) and G)
N) B) and J)

Question 6

Matching 
Choose the correct answer from the list. Not all the answers will be used.
-The enzyme ______ is unique because it contains an iron-sulfur cluster but does not participate in a redox reaction.

Accepted Answer

A)  oxaloacetate
B)  malate synthase
C)  malate
D)  malonate
E)  KrebsF) aconitaseG) succinyl-CoA synthetaseH) α-ketoglutarateI) carbon dioxideJ) malate dehydrogenaseK) isocitrateL) succinate dehydrogenaseM) E) and F)
N) A) and I)

Question 7

Which of the following is oxidized by a multienzyme complex that requires five different coenzymes?

Accepted Answer

A)   
B)   
C)   
D)  A and B
E)  A, B, and CF) A) and B)
G) C) and D)

Question 8

Which of the following structures represents a molecule that is added to succinate to form CoA and malate?

Accepted Answer

A)   
B)   
C)   
D)   
E)   F) All of the above
G) A) and D)

Question 9

The reaction catalyzed by pyruvate carboxylase is an example of a(n) ______ reaction because it replenishes the citric acid cycle intermediates that have been siphoned off for use in other reactions.

Accepted Answer

A)  amphibolic
B)  amphipathic
C)  anaplerotic
D)  cataplerotic
E)  none of the aboveF) A) and D)
G) C) and D)

Question 10

Which of the following is TRUE regarding the discovery of the citric acid cycle?
I.One of the first discoveries was the involvement of coenzyme A in the production of GTP.
II.Krebs had knowledge of the sequence of reactions before he was able to demonstrate the link of the cycle to glucose metabolism.
III.The citric acid cycle was the first cyclic pathway discovered.
IV.Krebs demonstrated the involvement of the citric acid cycle in oxidation of amino acid and fatty acids.

Accepted Answer

A)  I, II, III, IV
B)  I, II, III
C)  II, III
D)  III, IV
E)  II, IVF) B) and C)
G) B) and D)

Exam 17: Citric Acid Cycle

Which of the following is oxidized by a multienzyme complex that requires five different coenzymes?

Correct Answer
verified

Matching Choose the correct answer from the list. Not all the answers will be used. -The compound ______ is a structural analog and competitive inhibitor of the enzyme succinate dehydrogenase.

Correct Answer
verified

Matching Choose the correct answer from the list. Not all the answers will be used. -The enzyme ______ is unique because it contains an iron-sulfur cluster but does not participate in a redox reaction.

Correct Answer
verified

Which of the following structures represents a molecule that is added to succinate to form CoA and malate?

Correct Answer
verified

The reaction catalyzed by _____ requires an enzyme bound flavin coenzyme.

Correct Answer
verified

Which of the following coenzymes is required by E₁ of the pyruvate dehydrogenase complex for catalytic activity?

Correct Answer
verified

The reaction catalyzed by pyruvate carboxylase is an example of a(n) ______ reaction because it replenishes the citric acid cycle intermediates that have been siphoned off for use in other reactions.

Correct Answer
verified

Which of the following can be said about the isocitrate product of aconitase?

Correct Answer
verified

Correct Answer
verified

Considering the reactions within the citric acid cycle, which of the following molecules will be produced from the intermediate pictured on the right?

Correct Answer
verified

Exam 17: Citric Acid Cycle

Which of the following is oxidized by a multienzyme complex that requires five different coenzymes?

Correct AnswerverifiedShow Answer

Matching Choose the correct answer from the list. Not all the answers will be used. -The compound ______ is a structural analog and competitive inhibitor of the enzyme succinate dehydrogenase.

Correct AnswerverifiedShow Answer

Matching Choose the correct answer from the list. Not all the answers will be used. -The enzyme ______ is unique because it contains an iron-sulfur cluster but does not participate in a redox reaction.

Correct AnswerverifiedShow Answer

Which of the following structures represents a molecule that is added to succinate to form CoA and malate?

Correct AnswerverifiedShow Answer

The reaction catalyzed by _____ requires an enzyme bound flavin coenzyme.

Correct AnswerverifiedShow Answer

Which of the following coenzymes is required by E1 of the pyruvate dehydrogenase complex for catalytic activity?

Correct AnswerverifiedShow Answer

The reaction catalyzed by pyruvate carboxylase is an example of a(n) ______ reaction because it replenishes the citric acid cycle intermediates that have been siphoned off for use in other reactions.

Correct AnswerverifiedShow Answer

Which of the following can be said about the isocitrate product of aconitase?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Considering the reactions within the citric acid cycle, which of the following molecules will be produced from the intermediate pictured on the right?

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Which of the following coenzymes is required by E₁ of the pyruvate dehydrogenase complex for catalytic activity?

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified