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Alfred Hershey and Martha Chase examined transformation using bacteriophage (bacterial DNA virus) and bacterial cells.In this experiment,how is transformation (altered phenotype) displayed?


A) The bacteria are transformed (by phage DNA) into virus synthesizing cells.
B) The bacteria are transformed from live to dead by the virus.
C) The bacteria are transformed from rough to smooth by the virus.
D) The bacteria are transformed into a virus.
E) Transformation is not exhibited by a virus-infected bacterial cell.

F) C) and D)
G) None of the above

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Experiments on chromosome structure and function have shown that in eukaryotic chromatids:


A) there are at least 50 DNA molecules per chromatid.
B) there is more than one DNA replicating point per chromatid.
C) DNA molecules duplicate conservatively rather than semiconservatively.
D) DNA segregation to daughter chromatids occurs in a dispersive pattern.
E) most DNA synthesis occurs during the M (mitosis) phase of the cell cycle.

F) B) and C)
G) C) and D)

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Telomerase activity relies upon ________________ for appropriate priming.


A) RNA primase
B) a short,telomeric RNA sequence that is carried within its structure
C) a primosome subunit associated with the telomere structure
D) a unique protein-based primer
E) DNA polymerase III holoenzyme

F) B) and D)
G) A) and B)

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Linus Pauling proposed at one time that the DNA molecule was,in fact,a triple helix.If so,how would this situation affect cellular division?


A) The triple-helix DNA could be replicated and passed on to daughter cells as it normally would.
B) The triple-helix DNA could be replicated normally in mitosis but not meiosis.
C) Sperm and eggs produced by triple-helix DNA would be more fertile.
D) The fact that the DNA had three nucleotide strands would make it difficult to replicate the DNA and reassemble the copies.

E) C) and D)
F) B) and D)

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Alfred Hershey and Martha Chase examined transformation using bacteriophage (bacterial DNA virus) and bacterial cells.If phage are labeled with radioactive phosphate and allowed to infect bacterial cells,the radioactive phosphate will be localized to:


A) the inside of infected cells (in phage DNA) .
B) the outside of infected cells (in phage ghosts) .
C) newly synthesized phage viruses in the host bacterial cell.
D) No radioactivity will remain after infection.
E) The phosphate will be metabolically consumed,and therefore the radioactivity will be destroyed.

F) B) and C)
G) A) and E)

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If Escherichia coli,grown for a period of time in 15N,is transferred to 14N for one generation of DNA replication,the resulting DNA should have 14N added to all "new" DNA.If semiconservative replication is occurring,the 14N-containing "new" DNA will compose:


A) one strand of all bacterial chromosomes.
B) both strands of DNA in half of all bacterial chromosomes.
C) regions dispersed throughout all bacterial DNA.
D) none of the new DNA;it will only be found in the old DNA.
E) None of the answer options are correct.

F) D) and E)
G) A) and E)

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Alfred Hershey and Martha Chase examined transformation using bacteriophage (bacterial DNA virus) and bacterial cells.In these experiments,they used radioactivity to label nucleic acids (in this case DNA) and proteins.What do radioactive sulfur and phosphate specifically label?


A) Sulfur labels DNA,and phosphate labels protein.
B) Sulfur labels both protein and DNA.
C) Phosphate labels both protein and DNA.
D) Sulfur labels protein,and phosphate labels DNA.
E) None of the answer options are correct.

F) A) and B)
G) A) and C)

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When comparing the three key models of DNA replication,the model that included the synthesis of a brand new double-stranded DNA molecule from an original molecule was named:


A) dispersive replication.
B) conservative replication.
C) semiconservative replication.
D) liberal replication.
E) None of the answer options are correct.

F) A) and B)
G) B) and D)

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If Escherichia coli,grown for a period of time in 15N,is transferred to 14N for one generation of DNA replication,the resulting DNA should have 14N added to all "new" DNA.If conservative replication is occurring,the 14N-containing "new" DNA will compose:


A) one strand of all bacterial chromosomes.
B) both strands of DNA in half of all bacterial chromosomes.
C) regions dispersed throughout all bacterial DNA.
D) none of the new DNA;it will only be found in the old DNA.
E) All of the answer options are correct.

F) A) and E)
G) A) and B)

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Which of the following conditions is/are associated with abnormal telomerase activity resulting in premature aging?


A) Down syndrome
B) Patau syndrome
C) Cri-du chat syndrome
D) Werner syndrome

E) None of the above
F) All of the above

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