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What is a component of a single nucleotide?


A) A phosphate group
B) A six carbon sugar
C) All five nitrogenous bases

D) A) and C)
E) B) and C)

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What is one of the criteria that all genetic material must meet?


A) It does not contain the information necessary to construct the entire organism.
B) It must be passed from offspring to parent.
C) It must be able to be copied.
D) It must have a limited amount of variation.

E) All of the above
F) C) and D)

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C

The researcher(s) who initially used X-ray diffraction to gather information on the DNA molecule was ________.


A) Franklin
B) Watson and Crick
C) Hershey and Chase
D) Pauling
E) Chargaff

F) None of the above
G) A) and E)

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A

An RNA strand with sequence 5'-GUACAAUGACUUAUGUAC-3' can potentially form which structure?


A) Bulge loop
B) Internal loop
C) Multibranched junction
D) Stem-loop

E) A) and D)
F) A) and B)

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What was the conclusion of the Hershey-Chase experiments?


A) Their results suggested the presence of a transforming principle.
B) Their results suggested that DNA is a double helix.
C) Their results suggested that A+G=T+C.
D) Their results suggested that the DNA is the genetic material.

E) None of the above
F) A) and D)

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The fact that the helixes of the DNA strand are arranged in opposite directions gives DNA its ________ characteristics.


A) antiparallel
B) complementary
C) redundant
D) water-soluble

E) A) and C)
F) None of the above

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The ________ was labeled using the radioisotope 32P in the Hershey-Chase experiments.


A) RNA
B) DNA
C) protein
D) carbohydrates

E) B) and D)
F) A) and D)

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The pyrimidine bases are ________.


A) cytosine, thymine, and uracil
B) adenine and guanine
C) adenine and thymine
D) cytosine and guanine

E) A) and B)
F) B) and C)

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A nucleoside consists of only a five-carbon sugar and a phosphate group.

A) True
B) False

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In the Hershey-Chase experiments, the protein coat of the bacteriophage was labeled with the 32P radioisotope.

A) True
B) False

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Cells are treated with a drug that blocks purine synthesis. Which bases would not be made in those treated cells?


A) cytosine, thymine, and uracil
B) adenine and guanine
C) adenine and thymine
D) cytosine and guanine

E) C) and D)
F) B) and C)

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B DNA is recognized as a left-handed molecule.

A) True
B) False

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False

Which of the following is a correct matching of the researcher with their discovery?


A) Pauling provided information on primary structure in biological molecules.
B) Franklin suggested that DNA was a helix with more than one strand and that there were about 10 bases per turn of the DNA.
C) Watson and Crick collected a large amount of X-ray data on the structure of DNA.
D) Chargaff demonstrated that the adenine and cytosine bases and the uracil and guanine bases interacted in some manner.

E) A) and D)
F) B) and C)

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What were the conclusions of Franklin's work regarding the structure of DNA?


A) It did not have a helical structure.
B) The helix had more than one strand.
C) The helix contained about 1 bases per turn.
D) The helix had only one strand.

E) C) and D)
F) A) and B)

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What is the directionality of the DNA molecule?


A) Front to back
B) Top to bottom
C) 5' to 3'
D) 3' to 5'
E) All DNA molecules are different in their directionality

F) A) and D)
G) A) and C)

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The fact that the type R and S strains of Streptococcus pneumoniae that Griffith worked with possessed small differences in capsule structure satisfies which of the following criteria for genetic material?


A) Transmission
B) Replication
C) Information
D) Variation

E) B) and D)
F) A) and B)

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Which base is not found in DNA?


A) Cytosine
B) Guanine
C) Thymidine
D) Adenine
E) Uracil

F) C) and E)
G) A) and D)

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What is the most complex structure DNA can form?


A) Individual nucleotides
B) A folded and bended double helix
C) A single strand of DNA
D) A DNA double helix

E) A) and C)
F) A) and D)

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What is a characteristic of T2 bacteriophage?


A) It does not require a host cell for replication.
B) The phage attaches to the cell wall of a target eukaryotic cell.
C) The phages injects its DNA into the host cell.
D) The new phages are formed outside the host cell.

E) A) and B)
F) A) and C)

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Avery used the enzyme ________ to remove the proteins from the cell extracts.


A) protease
B) DNase
C) RNase
D) All of the answers are correct

E) A) and D)
F) B) and C)

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