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The strength of collagen comes from its:


A) triple helical structure and bundling.
B) amino acid sequence.
C) ability to bind to polysaccharide molecules.
D) triple helical structure and bundling, as well as its amino acid sequence.

E) B) and C)
F) None of the above

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Cells differentiate into multiple tissue types because each tissue has its own unique DNA.

A) True
B) False

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Imagine that you are examining a mouse that does not produce basal lamina in the skin. How will this mouse be different from a normal, wild-type mouse?


A) The epidermis will not be connected to the dermis.
B) The epidermis and dermis will be strongly connected.
C) The dermis will be disorganized and will lack blood vessels.
D) Cellular junctions will fail to form between the cells of the epidermis.
E) All of these choices are correct.

F) C) and D)
G) B) and C)

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Which of the following tissues would you expect NOT to be found in the human heart?


A) muscle
B) nervous
C) epithelial
D) connective
E) All of these tissues would be found in the human heart.

F) All of the above
G) B) and E)

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Which of the following statements about plant cell walls is NOT true?


A) The cell wall has three layers: the middle lamella, the primary cell wall, and the secondary cell wall.
B) In the late stages of cell division, the middle lamella is the first cell wall layer to be formed, serving to attach the daughter cells to each other.
C) The primary cell wall is thin and flexible, formed while the cells are still growing.
D) The secondary cell wall contains complex components such as lignin that are rigid.
E) Like the extracellular matrix formed by animal cells, the cell wall polymers are formed in the cytoplasm and secreted to the outside of the cell.

F) A) and B)
G) B) and E)

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Which of the following are components of the animal extracellular matrix?


A) cellulose and laminin
B) lignin and elastin
C) pectin and collagen
D) collagen and laminin
E) lignin and laminin

F) A) and D)
G) None of the above

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Which one of the cytoskeletal elements is associated with providing the cell with mechanical strength?


A) microtubules
B) microfilaments
C) microtubules and microfilaments
D) intermediate filaments

E) B) and D)
F) A) and C)

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Cancer can be characterized by:


A) a mass of rapidly dividing cells called a tumor.
B) metastasized tumor cells that leave the tumor and invade distant parts of the body.
C) cells with an enhanced ability to adhere to proteins in the basal lamina.
D) All of these choices are correct.

E) A) and D)
F) All of the above

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Which of the following properly groups a cell junction with a cytoskeletal structure and a cell adhesion molecule?


A) adherens junction, microfilament, integrin
B) hemidesmosome, intermediate filament, integrin
C) desmosome, intermediate filament, integrin
D) hemidesmosome, intermediate filament, cadherin

E) A) and D)
F) None of the above

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The cytoskeleton of plant cells includes:


A) microtubules, microfilaments, and intermediate filaments.
B) actin, microfilaments, and intermediate filaments.
C) actin, microtubules, and intermediate filaments.
D) tubulin, microfilaments, and intermediate filaments.
E) microtubules and microfilaments.

F) A) and B)
G) A) and C)

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Zebrafish embryos change the color of the melanophore cells in their skin to a darker shade by:


A) dynein motor proteins moving pigment granules outward from the center of the cell.
B) kinesin motor proteins moving pigment granules outward from the center of the cell.
C) dynein motor proteins moving pigment granules inward toward the center of the cell.
D) kinesin motor proteins moving pigment granules inward toward the center of the cell.
E) dynein motor proteins moving pigment granules inward toward the plus end of microtubules.

F) C) and D)
G) A) and E)

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Which of the following structures are responsible for the shape of a cell?


A) microvilli
B) cytoskeleton
C) cell junctions
D) organelles

E) B) and D)
F) All of the above

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Which of the following statements about cadherins and integrins is/are TRUE?


A) They are found on the surfaces of most animal cells.
B) They are transmembrane proteins that attach to cytoskeletal elements inside the cell.
C) They are highly specific for what their extracellular domain will attach to.
D) They are not found in embryonic cells.

E) A) and D)
F) B) and C)

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The epidermis contains several layers and receives its nutrients from the dermis by diffusion. Which of the following explains why the outermost layers of the epidermis consist of dead cells?


A) One of the major functions of the epidermis is forming a waterproof barrier. Once that barrier is formed, nutrients cannot pass through it and the cells beyond that layer die.
B) The protective function that the epidermis carries out is better served by having a layer of dead cells.
C) UV light cannot penetrate as easily through dead cells as it can through live cells.
D) None of the other answer options is correct.

E) C) and D)
F) A) and D)

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Microfilaments increase in length:


A) more quickly at one end than the other.
B) by assembling outward from the centrosome.
C) in cycles, following rapid depolymerization.
D) if free tubulin dimers are available.
E) All of these choices are correct.

F) A) and C)
G) A) and D)

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Which of the following statements about mammalian skin is INCORRECT?


A) The epidermis is an outer layer that provides a water-resistant, protective barrier.
B) The dermis is the layer below the epidermis containing connective tissue, blood vessels, and nerve endings that provides nutrients to the epidermis and a cushion layer for the body.
C) Epithelial cells in the epidermis are primarily composed of keratinocytes that protect underlying tissue.
D) A specialized form of extracellular matrix, called the basal lamina, underlies the dermis and separates it from tissues below.
E) Fibroblasts in the dermis produce extracellular matrix proteins to make the dermis strong and flexible.

F) A) and B)
G) A) and C)

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Flagella move in a(n) :


A) oarlike motion by the motor protein dynein sliding microtubules past each other.
B) oarlike motion by the motor protein kinesin sliding microtubules past each other.
C) whiplike motion by the motor protein dynein sliding microtubules past each other.
D) whiplike motion by the motor protein kinesin sliding microtubules past each other.
E) whiplike motion by the motor protein dynein sliding microfilaments past each other.

F) C) and D)
G) A) and B)

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Structures known as microvilli are associated with:


A) communication between cells.
B) increased surface area for gas exchange.
C) adhesion to the extracellular matrix.
D) increased surface area for nutrient absorption.

E) A) and B)
F) A) and D)

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Red blood cells are characterized as having an actin cytoskeleton associated with their plasma membrane. The presence of the membrane cytoskeleton MOST likely accounts for:


A) the shape of the cell.
B) enhanced gas exchange.
C) the ability of these cells to fit through narrow capillaries.
D) All of these choices are correct.

E) None of the above
F) A) and D)

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The extracellular matrix is composed of: (1) proteins; (2) polysaccharides; (3) nucleic acids.


A) Statement (1) is correct.
B) Statement (2) is correct.
C) Statement (3) is correct.
D) Statements (1) and (2) are correct.
E) All of these statements are correct.

F) A) and D)
G) A) and C)

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